CanRisk-Based Ovarian Cancer Risk Assessment Versus Standard Practice (DISARM CSA)

Official record

Identifier

NCT07809659

Recruiting locations

countries

CzechiaGreeceLithuaniaPortugal

Interventions studied

CanRiskStandard clinical risk assessment

Lead sponsor

Instituto Portugues Oncologia de Lisboa Francisco Gentil

Target enrolment

2130 participants

Study type

INTERVENTIONAL

Phase

Not applicable

Status

Recruiting

First posted

Sep 9, 2026

Last updated on the registry

Sep 29, 2026

Age

18 Years – 75 Years

Sex

FEMALE

Study contact

The official record lists a study contact. Contact details are published there and are intentionally not copied to this page.

Eligibility criteria

Reproduced verbatim from the official record. Eligibility is decided by the study team, never by this page.

Inclusion Criteria:

1. Women, trans men, non-binary people with female reproductive organs
2. Aged 18 to 75 years
3. Referred or self-referred because of a family history suggestive of increased risk for ovarian, fallopian tube or peritoneum cancer, or because a family member has been found to have a PV associated with OC risk
4. Able to give informed consent
5. Expected to remain in the study catchment area for the duration of follow-up.

Exclusion Criteria:

1. Personal history of cancer
2. Previously undergone Risk-Reducing Salpingo-Oophorectomy (RRSO)
3. Previously undergone multifactorial risk assessment (using CanRisk or another tool) incorporating risk factors, family history and genetic testing (panel +/- PGS)
4. Any condition or circumstance that, in the opinion of the investigator, could interfere with the participant's ability to participate or comply with study requirements

Indexed under

Ovarian Cancer