Prospective Evaluation of Hepatocellular Carcinoma Surveillance in At-Risk Patients (Screening HCC)

Official record

Identifier

NCT07764835

Recruiting locations

Locations are not included in the offline baseline for this record. Open the official record to see the current site list.

Interventions studied

Not provided in the official record

Lead sponsor

D'Or Institute for Research and Education

Target enrolment

300 participants

Study type

OBSERVATIONAL

Phase

Not provided in the official record

Status

Not yet recruiting

First posted

Aug 14, 2026

Last updated on the registry

Aug 14, 2026

Age

18 Years

Sex

ALL

Study contact

The official record lists a study contact. Contact details are published there and are intentionally not copied to this page.

Eligibility criteria

Reproduced verbatim from the official record. Eligibility is decided by the study team, never by this page.

Inclusion Criteria:

* Written informed consent.
* Age 18 years or older.
* Liver cirrhosis of any etiology.
* Chronic hepatitis B with moderate or high risk of HCC according to PAGE-B criteria.
* Non-cirrhotic chronic liver disease with increased risk for HCC, including fibrosis stage 3 or higher or metabolic dysfunction-associated steatotic liver disease (MASLD) with one or more risk factors for HCC.
* Followed at hepatology clinics within the Rede D'Or health network.
* Eligible for routine HCC surveillance with ultrasound and alpha-fetoprotein according to standard clinical practice.

Exclusion Criteria:

* Known hepatocellular carcinoma at enrollment.
* Previous diagnosis of hepatocellular carcinoma.
* Metastatic liver disease.
* Other malignant liver tumors present at enrollment.
* Clinical condition preventing routine surveillance follow-up.
* Inability to provide informed consent.

Indexed under

Liver Cancer