USClinicalTrials.govClinical trialActive, not recruiting
Streamlined Resin Y90 Radiation Segmentectomy for Small HCC
Official record
- Identifier
NCT06618300- Recruiting locations
country
United States- Interventions studied
- Not provided in the official record
- Lead sponsor
- UNC Lineberger Comprehensive Cancer Center
- Target enrolment
- 30 participants
- Study type
- OBSERVATIONAL
- Phase
- Not provided in the official record
- Status
- Active, not recruiting
- First posted
- Oct 1, 2024
- Last updated on the registry
- Aug 13, 2026
- Age
- 18 Years
- Sex
- ALL
- Study contact
- No public contact is listed on the official record.
- Eligibility criteria
Reproduced verbatim from the official record. Eligibility is decided by the study team, never by this page.
Inclusion Criteria: * 18 years of age or older * Has focal Hepatocellular Carcinoma and is deemed to benefit from Yttrium-90 radioembolization by the institutional multidisciplinary tumor board Exclusion Criteria: * All subjects meeting any of the exclusion criteria at baseline will be excluded from study participation. * The presence of trans-jugular intrahepatic portosystemic shunt * Total bilirubin level \> 3.0 mg/dL * Serum albumin level \< 2.5 g/dL * Aspartate and alanine aminotransferase levels no greater than five times the normal level * Life expectancy \< 12 weeks * Eastern Cooperative Oncology Group performance status \> 2 * Patients with chronic lung disease requiring supplemental oxygen at baseline or baseline SpO2 of \<92% * Patients that have tumors with central anatomical locations close the hepatic hilum or caudate lobe. * Patients with macrovascular invasion on baseline imaging * Known hypersensitivity to iodinated contrast agents or to any component of iodinated contrast agents refractory to standard medications (antihistamines, steroids) * Impaired kidney function (glomerular filtration rate \< 30 as approximated using serum creatinine levels) unless anuric and on dialysis. * Any woman who is pregnant or has reason to believe she is pregnant (the possibility of pregnancy has to be excluded by negative urine β-HCG results, obtained within 48 hours prior to the treatment or on the basis of patient history, e.g.: tubal ligation, hysterectomy or a minimum of 1 year without menses)
- Indexed under
- Liver Cancer