Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

Official record

Identifier

NCT05237986

Recruiting locations

country

United States

Interventions studied

Not provided in the official record

Lead sponsor

National Cancer Institute (NCI)

Target enrolment

60 participants

Study type

OBSERVATIONAL

Phase

Not provided in the official record

Status

Recruiting

First posted

Feb 14, 2022

Last updated on the registry

Aug 31, 2026

Age

5 Years

Sex

ALL

Study contact

The official record lists a study contact. Contact details are published there and are intentionally not copied to this page.

Eligibility criteria

Reproduced verbatim from the official record. Eligibility is decided by the study team, never by this page.

* INCLUSION CRITERIA:
* Participants with disease

  * Participants are diagnosed with relapsed/refractory leukemias or lymphomas, and are scheduled to receive CAR T-cell treatment in one of the enrolling sites
  * For participants enrolled on a CAR T-cell treatment protocol, data sharing for the purposes of this study must be allowed.
  * Age \>= 5 and \<=35 years old
  * Participant must have an eligible caregiver (informant) who is willing to complete assessments about the participant of this study
  * Participants (\<18 years, or \>=18 years if needed) must have an eligible caregiver to assist with setting up an appropriate test environment for the remote evaluations
  * Participant must be able to speak and understand English or Spanish
  * Participants must have access to a computer or tablet with a camera and an internet connection
  * Participant or parent/guardian must be able to understand and willing to sign a written consent document
* Caregivers (informants)

  * Participants must be able to speak and read in English or Spanish
  * Participants who are caregivers for participants with disease addressed above
  * Age \>= 18 years old
  * Participants must have access to a computer or tablet
  * Participants (of children \<18 years, or \>18 years if needed) must be willing to help set up an appropriate test environment for the remote evaluations
  * Participant is able to understand and willing to sign a written consent document

EXCLUSION CRITERIA:

-Participants with disease who have a pre-existing global intellectual disability (e.g., Down Syndrome)

Indexed under

Lymphoma